The Centres for Disease Control has declared that HIV patients cannot transmit the virus to sexual partners if they have suppressed their viral load with medication.
Until now, the agency has refused to say for certain that people who religiously take HIV drugs are not a danger to society.
But for years, activists and researchers have been campaigning for that to change since every clinical trial and cohort study ever conducted shows those with an “undetectable” virus have a zero percent risk of transmission.
The move, announced in a letter recently has been hailed as a “breakthrough against stigma and for HIV prevention” by the HIV community.
It means the Centres for Disease Control and Prevention has joined scores of public health agencies and more than 400 organisations from nearly 60 countries in affirming that people who take medication are not dangerous to sexual partners.
A person with HIV becomes “undetectable” when treatment suppresses the virus to a level so low in their blood that it cannot be detected by measurements.
Scores of studies on more than 58 000 sex acts have shown that if a person is undetectable and stays on treatment, they cannot pass HIV on to a partner.
The strength of this association first became clear a few years ago, and gradually health officials have been acknowledging the results.
Dr Anthony Fauci, head of the HIV/Aids division at the National Institutes of Health, was the first high-level figure to back the statement that “U=U” (undetectable equals untransmittable).
Finally, on September 27, Dr Jonathan Mermin, Director of National Centre for HIV/Aids, Viral Hepatitis, STD and TB Prevention; and Dr Eugene McCray, Director Division of HIV/Aids Prevention at the Centres of Disease Control and Prevention made their statement.
Their letter read: “People who take ART (anti-retroviral therapy) daily as prescribed and achieve and maintain an undetectable viral load have effectively no risk of sexually transmitting the virus to an HIV-negative partner.”
Speaking to Daily Mail Online, Dr Fauci emphasised the gravity of their statement.
“They have never said undetectable equals untransmittable. They have explained the data and acknowledged findings of cohort studies and clinical trials, but they have never come out and said it the way the gay community wanted to hear it. That is huge.
“When you’re dealing with biology, people are really concerned with the exceptions. But when you make recommendations for people’s health, you have to go with the overwhelming data. Maybe once in a while there might be an exception but that is always down to a mistake — the person thinks they’re undetectable when they’re not, or they are not taking their medication as they should. If you are truly undetectable there is no risk of transmission.”
Previously, public health officials have cited concerns that we need to explore more precise HIV testing methods to detect hidden traces of the virus. Trials are under way to explore how the virus could linger in sperm, for example.
While those concerns are valid, the CDC and NIH have concluded that even though someone with HIV could have hidden reservoirs of the virus, there is conclusive evidence that those traces are not viable and cannot be transmitted.
Dr Fauci said the CDC’s statement will have a two-fold positive effect: dispelling societal stigma and personal stigma.
“No one should ever underestimate the concern about social stigma — the pressure people put on themselves,” Dr Fauci explained. There are people out there who have guilt and fear about getting tested positive. They are afraid of the stigma of being positive, so they may not get tested.
“But now, if you know that by taking medication you are dangerous to nobody, that does have a profound impact psychologically. People won’t be afraid to get tested and start medication so they can suppress their viral load.”
Bruce Richman, founder of Prevention Access Campaign which has pioneered the push to recognise U=U, told Daily Mail Online: “This is a new world for people living with HIV. It’s history-making because it changes what it means to live with HIV and HIV prevention. It removes so much of the HIV stigma, fear and shame that millions have lived and died with for the past 35 years.
“Now we need to make sure everyone living with HIV has access to the treatment and care to keep them and their partners healthy and make HIV history.” To date, an undetectable load is almost always achieved with daily doses of anti-retroviral drugs.
But a number of clinical trials —including PRO-140 by CytoDyn, which Charlie Sheen is involved in — hope to be developing treatments that could be administered on a weekly or fortnightly basis. — Daily Mail
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